T.R. Knight is best known for his role on Grey’s Anatomy, but what has the actor been up to since leaving the Shonda Rimes medical drama? Knight was one of the original Grey’s Anatomy cast members and made his debut as George O’Malley in the show’s first-ever episode back in 2005. What Knight assumed would be a one-season stint eventually turned into a five-season run, during which he received positive reviews and a Primetime Emmy nomination for Outstanding Supporting Actor for his performance as George.
Over the course of his five seasons on Grey’s Anatomy, T.R. Knight saw his character evolve from a nervous medical intern into a competent, talented doctor who enjoyed multiple relationships with his fellow residents, including Meredith Grey (Ellen Pompeo), Izzie Stevens (Katherine Heigl) and Callie Torres (Sara Ramirez). Knight left the show after the fifth season of Grey’s Anatomy when George died after being hit by a bus in the season finale.
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T.R. Knight has enjoyed a steady stream of work since departing Grey’s Anatomy. Immediately after the show he returned to his roots as a stage actor, starring in a production of the musical Parade at the Mark Taper Forum in Los Angeles in 2009 before appearing opposite Patrick Stewart in a Broadway production of A Life In The Theatre the following year. Knight followed up with a dual role as twin brothers in a season 13 episode of Law & Order: SVU and later joined the cast of The Good Wife in a recurring season 4 role as campaign manager Jordan Karahalios.
He’s had roles in films like 42, A Year And Change and Hello Again but TV work has been Knight’s bread and butter. He played Johnny Clayton in the Stephen King-based miniseries 11.22.63 and reunited with Rimes on comedy-drama The Catch playing Tommy Vaughan. He’s taken on quite a few biographical roles as well, playing LGBT activist Chad Griffin in the docudrama miniseries When We Rise and FBI founder J. Edgar Hoover and French poet-painter Max Jacob in different seasons of Genius. In 2019, he turned his hand to voice acting with a role on Hulu animated series The Bravest Knight as Sir Cedric.
More recently, T.R. Knight played Donald Trump’s former chief of staff Reince Priebus in political drama miniseries The Comey Rule and appeared in an episode of Will & Grace’s eleventh and final season as a writer from the New York Gayzette who interviews Jack (Sean Hayes). Knight made a brief return to Grey’s Anatomy in its most recent season, reprising the role of George in one of Meredith Grey’s COVID-19-induced fever dreams. Currently, T.R. Knight is starring in the HBO Max comedy-drama series The Flight Attendant as Davey Bowden, the brother of main character Cassie Bowden (Kaley Cuoco). Considering HBO recently renewed the show for a second season, it’s likely we’ll be seeing more of Knight in The Flight Attendant in the not-too-distant future.